BTOES Insights Official
May 19, 2022


Courtesy of Sanofi's Vatsala Sadasivan below is a video of his speaking session on 'Empowering Excellence in R&D' to Build a Thriving Enterprise that took place at Business Transformation & Operational Excellence Summit Healthcare Live - A Virtual Conference.

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Session Information:

Empowering Excellence in R&D

“We can do better science by operating more efficiently”

The biopharmaceutical R&D value stream process is complex, lengthy (10 years on average to develop a biologics drug from discovery to commercial launch) and highly matrixed. It consists of technical processes which interface with various business processes needed to enable the drug development process.

In addition, the R&D environment naturally focuses on “scientific excellence” and faces cultural challenges to embrace “operational excellence”. Thus, the long lead time to develop a drug combined with the high matrix interfaces and cultural barriers makes it challenging to develop an operational excellence roadmap for R&D. The road to operational excellence in R&D is very young and more complex compared to the manufacturing and service businesses

  • requires adaptation of traditional approaches to fit the R&D processes

  • requires transversal collaboration to be successful

  • requires a cultural change within the organization

Btog CTA

This presentation will demonstrate the impact of Operational Excellence for R&D, in terms of transforming R&D into a highly efficient organization and enabling scientific excellence in R&D. It will show you how to build your own roadmap for empowering excellence in the R&D environment, which will include the following

  • overview of the biopharmaceutical R&D process

  • challenges in applying operational excellence in R&D

  • how to develop a strategic Operational Excellence roadmap in R&D

  • examples of case studies

Session Video:


To view all Business Transformation & Operational Excellence Summit Healthcare Live Sessions Recording Please click below:

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To View All Events Recorded Sessions Please Click Below:

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About the Author

more-May-19-2022-12-29-58-70-PMVatsala Sadasivan,
Operational Excellence Lead, R&D North America,


Vatsala is a strategy, innovation and operational excellence leader with business, technical and organizational skills focusing in the biopharmaceutical industry, with 16+ years of experience. She has worked in 4 different biopharmaceutical companies, from R&D to clinical and commercial manufacturing operations.

Worked in 4 different biopharmaceutical companies across 3 continents. Skilled at driving transformation roadmaps from R&D to commercial manufacturing. Expertise around process simplification and optimization, implementation of best in-class technology and digital solutions and developing high performing organizations. A strategic thinker who is able to translate vision and strategy into operational solutions. Passionate about innovation and technology, global networking, benchmarking and experience in multicultural environments (North America, South America, Europe and Asia).

Vatsala is currently the Operational Excellence Lead for Sanofi’s R&D North America Hub, where she is responsible for driving Operational Excellence roadmaps in North America and global R&D. Prior to her current role, she held various Operational Excellence roles within Sanofi Genzyme in the Commercial Manufacturing Operations business. Before joining Sanofi Genzyme, Vatsala worked for Shire and Millipore in various functions from R&D to clinical and commercial manufacturing operations.

She holds a Masters in Chemical Engineering from Northeastern University-Boston and Bachelors in Chemical Engineering from the University of Nebraska-Lincoln. She has a digital mindset and is passionate about AI applications for the life science industry and has completed the Executive Program in Artificial Intelligence - Implications for Business Strategy from the MIT Sloan School of Management.


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